Figure 1.

Chemoresistance of ATN-1 cells co-cultured with macrophages. (A) Method of adult T-cell leukemia/lymphoma (ATLL) cell isolation following co-culture with macrophages. (B) Following co-culture with macrophages for 3 weeks, the ATN-1 cells were incubated with the anticancer agents carboplatin (CBDCA) and Adriamycin (ADR) for 24 h. The sensitivity of the ATN-1 cells to CBDCA and ADR was then evaluated using a WST assay. PBS, phosphate-buffered saline; CD, cluster of differentiation; Ab, antibody.