Table 1.

Summary of Fc receptor-like proteins. This chart gives a summary of each FCRL protein and its known ligands, cellular distribution, and association with different diseases.

	Ligands	Cellular Distribution	Associated Diseases
FCRL1	Unknown	Broad B cell expression [10,11]	Burkitt Lymphoma CLL
FCRL2	Unknown	Memory B cells [11] Circulating Marginal Zone B cells	IGHV CLL
FCRL3	Unknown	Memory B cells [16] Circulating Marginal Zone B cells [16] T cells [11] NK cells C	Autoimmunity
FCRL4	Heat-aggregated IgA	Memory B cells Tissue-based Marginal Zone B cells [17]	HIV Hepatitis C MZ Lymphomas
FCRL5	Heat-aggregated IgG	Naive B Cells [11]Memory B Cells [11] Plasma Cells [11]	Burkitt Lymphoma
FCRL6	MHC Class II/HLA-DR, Intracellular IgM and IgG	Cytotoxic T cells [22] NK Cells [22]	HIV-1
FCRLA	Intracellular IgM, IgG, and IgA	Germinal Center B cells	Unknown
FCRLB	Unknown	Germinal Center B cells	Unknown