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. 2016 Jul 19;11(7):e0159507. doi: 10.1371/journal.pone.0159507

Fig 2. Epigenetic regulator expression in individual human blastocysts by qPCR (n = 12 replicates for each group).

Fig 2

Ct values were normalized to RPL19, an internal, constant housekeeping gene. Fold change was determined using the ΔΔCt method on the average of technical duplicates. Error bars represent standard error and the y-axis denotes fold change between euploid and aneuploidy. A) The expression of DNA methylatransferases was analyzed in euploid, trisomy 15, and monosomy 15 blastocysts (*P < 0.05). B) The expression of post-translational regulators and the chromatin modifying protein, PRMT5 (*P < 0.05).