Table 3. Methylome profiles of pooled human blastocysts (n = 10 each pool with 2–3 replicates per group).
Beta value reflects the level of global methylation with no variation observed in association with blastocyst chromosome constitution. (no statistical significance). Standard deviation (STDEV) was calculated for each group, reflecting low biological variability between replicates.
| Group | Beta Value | STDEV |
|---|---|---|
| (Avg) | ||
| Diploid (Euploid) | 0.21 | 0.01 |
| Trisomy 7 | 0.21 | 0.01 |
| Trisomy 11 | 0.20 | 0.01 |
| Trisomy 15 | 0.20 | 0.01 |
| Trisomy 21 | 0.20 | 0.01 |
| Trisomy 22 | 0.20 | 0.01 |
| Monosomy 7 | 0.20 | 0.01 |
| Monosomy 11 | 0.20 | 0.06 |
| Monosomy 15 | 0.20 | 0.00 |
| Monosomy 21 | 0.20 | 0.01 |
| Monosomy 22 | 0.21 | 0.00 |