Table 2. Protein features and transcriptional profiles of selected candidate genes.

Pf Gene Name	Protein Feature				Upregulated transcription in LS vs
	Protein Length	TM	SP	PEXEL/VTS	BS	SS
PF3D7_0304600 (CSP)	397	1	1	2	Yes	No
PF3D7_0730200a	858	0	0	0	Yes	Yes
PF3D7_1323000a	230	1	1	0	Yes	Yes
PF3D7_1411500a	947	0	0	0	Yes	Yes
PF3D7_1418100 (LISP1)a	3597	0	0	0	Yes	Yes
PF3D7_1207400a	395	0	0	0	Yes	No
PF3D7_1241500a	420	0	0	0	Yes	Yes
PF3D7_1308500b	359	0	0	0	Yes	No
PF3D7_0727200b	553	0	0	1	Yes	No
PF3D7_0818900b	677	0	0	1	Yes	Yes
PF3D7_1111200b	594	0	0	0	Yes	Yes
PF3D7_1122200b	446	0	0	0	Yes	Yes
PF3D7_1134000b	663	0	0	0	Yes	Yes
PF3D7_1147000 (SLARP)b	2940	0	0	0	Yes	No
PF3D7_1302200b	229	2	1	0	Yes	No
PF3D7_1434400b	285	1	0	0	Yes	No
PF3D7_1456100b	462	0	0	0	Yes	Yes
PF3D7_0103400b	1620	0	0	0	Yes	No
PF3D7_0304300b	1429	0	0	0	Yes	Yes
PF3D7_0405500b	224	0	0	1	Yes	Yes
PF3D7_0506200b	327	0	0	0	Yes	Yes
PF3D7_1026400c	603	0	0	0	Yes	No

^aProtective in both models

^bProtective in one model

^cProtective in neither model

CSP as a positive control.