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. 2016 Jul 19;11(7):e0158746. doi: 10.1371/journal.pone.0158746

Fig 5. Immunomodulatory properties of MSCs.

Fig 5

(A-C) Expression of mRNA for TGF-β, IL-10 and IDO measured by real-time RT-PCR in control (C, white bars) and MSCs (yellow bars) stimulated with IFNγ and TNFα after 3, 6, 12 and 24 h. *P<0.05 vs control cells. Expression of mRNA for (D-G) NK1-R, NK2-R, VIP and CGRP measured by real-time RT-PCR in control, OVA and OVA+MSCs groups. Three sets of MSCs were used for in vitro experiments. Four to seven animals were used for PCR analysis of neuropepetides. TGF-β: transforming growth factor-β; IDO: indoleamine 2,3-dioxygenase; CGRP: calcitonin gene-related peptide; VIP: vasoactive intestinal peptide; NK1-R; neurokinin 1 receptor; NK2-R: neurokinin 2 receptor.