Table 2. Risk Factors and Level of Assessed Risk Among Patients With Atrial Fibrillation in Intervention and Control Arms of a Cluster-Randomized Controlled Trial of a Computerized Antithrombotic Risk Assessment Tool for General Practitioners in New South Wales, Australiaa .
Risk Factor and Level | All Patients (N = 393) | Intervention Arm (n = 206) | Control Arm (n = 187) | P Valueb |
---|---|---|---|---|
Stroke Riskc | ||||
Risk factor | ||||
Previous stroke or transient ischemic attack | 72 (18.3) | 50 (24.3) | 22 (11.8) | .001 |
Aged ≥75 y | 266 (67.7) | 151 (73.3) | 115 (61.5) | .01 |
Congestive heart failure | 100 (25.4) | 84 (40.8) | 16 (8.6) | <.001 |
Hypertension | 268 (68.2) | 166 (80.6) | 102 (54.5) | <.001 |
Diabetes mellitus | 78 (19.8) | 41 (19.9) | 37 (19.8) | 0.98 |
Level of assessed risk | ||||
High | 278 (70.7) | 175 (85.0) | 103 (55.1) | <.001 |
Intermediate | 88 (22.4) | 25 (12.1) | 63 (33.7) | |
Low | 27 (6.9) | 6 (2.9) | 21 (11.2) | |
Bleeding Risk d | ||||
Risk factor | ||||
Hepatic or renal disease | 18 (4.6) | 12 (5.8) | 6 (3.2) | .22 |
Alcohol abuse | 8 (2.0) | 7 (3.4) | 1 (0.5) | .045 |
Malignancy | 33 (8.4) | 22 (10.7) | 11 (5.9) | .09 |
Reduced platelet count | 6 (1.5) | 6 (2.9) | 0 (0.0) | .02 |
Re-bleeding risk | 4 (1.0) | 4 (1.9) | 0 (0.0) | .06 |
Uncontrolled hypertension | 40 (10.2) | 13 (6.3) | 27 (14.4) | .008 |
Anemia | 14 (3.6) | 9 (4.4) | 5 (2.7) | .36 |
Risk of excessive falls | 22 (5.6) | 22 (10.7) | 0 (0.0) | <.001 |
Previous hemorrhagic stroke | 6 (1.5) | 6 (2.9) | 0 (0.0) | .02 |
Level of assessed risk | ||||
High | 4 (1.0) | 4 (1.9) | 0 (0.0) | .03 |
Intermediate | 10 (2.5) | 8 (3.9) | 2 (1.1) | |
Low | 379 (96.4) | 194 (94.2) | 185 (98.9) |
All values are number (percentage in subgroup) unless otherwise indicated.
P value for difference between intervention arm and control arm determined by Pearson χ2 test.
Patients were assessed for risk of stroke according to the CHADS2 Score for Atrial Fibrillation Stroke Risk (25).
Patients were assessed for risk of bleeding according to HEMORR2HAGES criteria (26).