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. 2016 Jul 14;13:E90. doi: 10.5888/pcd13.160078

Table 3. Medication-Safety and Medication-Management Assessments in the Intervention and Control Arms of a Cluster-Randomized Controlled Trial of a Computerized Antithrombotic Risk Assessment Tool for General Practitioners in New South Wales, Australiaa .

Assessment All Patients (N = 393) Intervention Arm (n = 206) Control Arm (n = 187) P Valueb
Medication safety
Patient allergic to warfarin and aspirin 8 (2.0) 6 (2.9) 2 (1.1) .22
Adverse reaction to antithrombotics 15 (3.8) 9 (4.4) 6 (3.2) .52
Taking medication that interacts with warfarin 1 (0.3) 1 (0.5) 0 (0.0) .73
Patient has declined antithrombotics 5 (1.3) 4 (1.9) 1 (0.5) .38
Patient has contraindication to antithrombotics 11 (2.8) 5 (2.4) 6 (3.2) .76
Patient has failed antithrombotics 10 (2.5) 6 (2.9) 4 (2.1) .75
Patient received education about antithrombotics 380 (96.7) 198 (50.4) 182 (47.9) .58
Medication management
Patient taking ≥4 medications 371 (94.4) 195 (94.7) 176 (94.1) .83
Patient is not compliant with medication 22 (5.6) 8 (3.9) 14 (7.5) .13
Patient needs assistance for medication management 161 (41.0) 83 (40.3) 78 (41.7) .84
Difficulty accessing medical care 3 (0.8) 1 (0.5) 2 (1.1) .61
Patient in residential care facility 4 (1.0) 2 (1.0) 2 (1.1) >.99
Cognitive impairment 18 (4.6) 8 (3.9) 10 (5.3) .63
Vision impairment 24 (6.1) 15 (7.3) 9 (4.8) .40
Hearing impairment 34 (8.7) 18 (8.7) 16 (8.6) >.99
Language/communication barrier 4 (1.0) 2 (1.0) 2 (1.1) >.99
Mobility disorder 17 (4.3) 9 (4.4) 8 (4.3) >.99
Functional impairment 63 (16.0) 26 (12.6) 37 (19.8) .06
a

All values are number (percentage in subgroup) unless otherwise indicated.

b

P value for difference between intervention arm and control arm determined by Pearson χ2 test.