TABLE 2.
1-y Outcome
|
2-y Outcome
|
Group × Time (Baseline vs 1-y)
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Group × Time (Baseline vs 2-y)
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A/M (N =23)
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ESDM (N =24)
|
A/M (N =21)
|
ESDM (N =24)
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Mean | SD | Δ | Mean | SD | Δ | Mean | SD | Δ | Mean | SD | Δ | F | MS | P | F | MS | P | |
Chronological age, mo | 38.1 | 3.8 | 15.3 | 38.8 | 4.4 | 14.9 | 52.1 | 4.3 | 29.3 | 52.4 | 3.4 | 28.5 | 0.95 | 2.18 | .334 | 1.27 | 6.91 | .266 |
MSEL | ||||||||||||||||||
Early-learning composite | 64.0 | 13.8 | 4.4 | 76.4 | 23.4 | 15.4 | 66.3 | 15.3 | 7.0 | 78.6 | 24.2 | 17.6 | 5.99 | 1416.90 | .018 | 4.31 | 1264.38 | .044 |
Receptive language | 31.1 | 11.1 | 9.8 | 38.9 | 15.4 | 17.8 | 31.5 | 10.6 | 10.2 | 40.0 | 16.3 | 18.9 | 4.00 | 745.21 | .051 | 4.14 | 843.56 | .048 |
Expressive language | 33.0 | 11.5 | 6.7 | 36.1 | 14.2 | 11.6 | 30.0 | 9.2 | 4.0 | 36.6 | 13.6 | 12.1 | 1.99 | 290.43 | .165 | 4.88 | 748.07 | .033 |
Visual reception | 29.0 | 10.7 | −1.7 | 38.8 | 16.4 | 5.6 | 34.5 | 13.0 | 4.5 | 41.0 | 17.9 | 7.8 | 4.22 | 621.97 | .046 | 0.63 | 126.23 | .433 |
Fine motor | 26.1 | 8.6 | −5.0 | 32.7 | 11.7 | −1.3 | 28.5 | 9.5 | −2.8 | 33.5 | 12.2 | −0.4 | 1.32 | 161.35 | .256 | 0.46 | 63.81 | .503 |
VABS | 63.7 | 8.8 | −6.3 | 65.7 | 9.8 | −3.8 | 59.1 | 8.8 | −11.2 | 68.7 | 15.9 | −0.8 | 0.85 | 71.61 | .360 | 7.05 | 1181.82 | .011 |
Communication | 71.0 | 13.0 | 1.2 | 73.5 | 11.7 | 5.0 | 69.4 | 15.8 | −0.7 | 82.1 | 21.8 | 13.7 | 1.38 | 175.69 | .246 | 6.38 | 2300.98 | .015 |
Socialization | 68.9 | 12.1 | −3.5 | 70.0 | 9.9 | −3.8 | 63.1 | 9.3 | −8.9 | 69.2 | 11.6 | −4.6 | 0.01 | 1.15 | .934 | 1.29 | 204.57 | .263 |
Daily living skills | 65.3 | 7.1 | −7.4 | 65.6 | 8.6 | −5.3 | 58.0 | 8.1 | −14.5 | 64.7 | 12.4 | −6.2 | 0.89 | 51.78 | .350 | 6.73 | 773.34 | .013 |
Motor skills | 70.7 | 12.2 | −15.9 | 75.1 | 14.4 | −12.2 | 64.1 | 12.3 | −23.1 | 77.4 | 19.8 | −9.9 | 0.99 | 157.43 | .326 | 7.40 | 1881.65 | .009 |
ADOS severity score | 7.3 | 2.1 | 0.4 | 6.5 | 1.5 | −0.7 | 7.3 | 1.8 | 0.3 | 7.0 | 1.9 | −0.2 | 3.38 | 13.15 | .072 | 0.66 | 3.29 | .422 |
RBS total | 23.3 | 17.5 | 1.0 | 15.5 | 12.3 | 0.9 | 22.0 | 16.3 | −0.6 | 16.7 | 13.1 | 2.5 | 0.001 | 0.19 | .976 | 0.37 | 92.50 | .545 |
Δ indicates mean change from baseline.