Table 2. Folate receptor-α expression in NSCLC.
| Total No. | FRα(+) No. (%) | FRα(−) No. (%) | P-value | |
|---|---|---|---|---|
| Biopsies | ||||
| Total | 23 | |||
| Adenocarcinoma | 12 | 8 (67) | 4 (33) | 0.036 |
| SCC | 11 | 2 (18) | 9 (82) | |
| Primary tumor | ||||
| Total | 60 | |||
| Adenocarcinoma | 34 | 21 (62) | 13 (38) | <0.001 |
| SCC | 26 | 4 (15) | 22 (85) | |
| Lymph node metastases | ||||
| Total | 60 (in 33 pts) | |||
| Adenocarcinoma | 42 (in 18 pts) | 26 (62) | 16 (38) | 0.004 |
| SCC | 18 (in 15 pts) | 3 (17) | 15 (83) | |
| Distant metastasis | ||||
| Total | 23 | |||
| Adenocarcinoma | 15 | 5 (33) | 10 (67) | 0.122 |
| SCC | 8 | 0 (0) | 8 (100) |
Abbreviations: SCC squamous cell carcinoma; FRα Folate receptor α; pts patients