Table 4. Folate receptor-α expression in breast cancer patients.
| Biopsy | Biomarker status | FRα(+) No. (%) | FRα(−) No. (%) | P-value |
|---|---|---|---|---|
| Total | 12 | 28 | ||
| HR status | positive | 1 (8) | 18 (64) | 0.002 |
| negative | 11 (92) | 10 (36) | ||
| HER2 status | positive | 5 (42) | 12 (43) | 1.000 |
| negative | 7 (58) | 16 (57) | ||
| TN | yes | 7 (58) | 8 (29) | 0.091 |
| no | 5 (42) | 20 (72) | ||
| Node status | positive | 7 (58) | 20 (71) | 0.476 |
| negative | 5 (42) | 8 (29) | ||
| Lumpectomy specimen | ||||
| Total | 20 | 20 | ||
| HR status | positive | 5 (25) | 6 (30) | 0.010 |
| negative | 15 (75) | 14 (70) | ||
| HER2 status | positive | 7 (35) | 10 (50) | 0.523 |
| negative | 13 (65) | 10 (50) | ||
| TN | yes | 12 (60) | 3 (15) | 0.008 |
| no | 8 (40) | 17 (85) | ||
| Node status | positive | 12 (60) | 15 (75) | 0.501 |
| negative | 8 (40) | 5 (25) | ||
| Lymph node metastasis | ||||
| Total | 6 | 14 | ||
| HR status | positive | 2 (33) | 7 (50) | 0.642 |
| negative | 4 (67) | 7 (50) | ||
| HER2 status | positive | 2 (33) | 8 (57) | 0.628 |
| negative | 4 (67) | 6 (43) | ||
| TN | yes | 3 (50) | 4 (29) | 0.613 |
| no | 3 (50) | 10 (71) |
Abbreviations: FRα Folate receptor α; HR hormone receptor including estrogen- and progesterone receptor; HER2 human epidermal growth factor receptor 2; TN triple negative