Table 2. Clinico-pathological characterization of the melanoma patients treated with radiotherapy.
| Features | Cohort A | Cohort B |
|---|---|---|
| Age (yrs) | 56.0 (25.7–83.6) | 59.0 (22–100) |
| Gender | ||
| F | 22 | 41 |
| M | 35 | 43 |
| Therapy | ||
| Only surgery | 0 | 53 |
| Only CHTH | 0 | 9 |
| Only RTH | 33 | 11 |
| RTH and CHTH | 24 | 11 |
| Melanization | Metastatic melanomas | Primary/metastatic melanomas# |
| Amelanotic | 34 | 35/15 |
| Melanin level 0 | 25 | 20/15 |
| Melanin level 1f | 9 | 15/0 |
| Pigmented | 23 | 49/18 |
| Melanin level 1d | 3 | 5/4 |
| Melanin level 2 | 5 | 15/3 |
| Melanin level 3 | 4 | 14/2 |
| Melanin level 4 | 2 | 14/4 |
| Melanin level 5 | 9 | 1/5 |
| pT | ||
| pT1 | –* | 29 |
| pT2 | –* | 10 |
| pT3 | –* | 13 |
| pT4 | –* | 32 |
| pN | ||
| pN0 | –* | 57 |
| pN1 | –* | 11 |
| pN2 | –* | 11 |
| pN3 | –* | 5 |
CTHT-chemotherapy; RTH-radiotherapy; 1f - melanin content defined as 1 but with focal distribution; 1d - melanin content defined as 1 but with dispersed distribution
*
the data related to pT and pN status of patients in cohort A qualified for RTH treatment are incomplete since 68% of primary lesions were diagnosed in other hospitals and histopathological examination reports were not accessible
#
number of metastases includes both melanoma metastases resected at the time of primary diagnosis (n = 27) and during the follow-up (n = 6).