Table 4. Multivariate prognostic analysis of progression-free survival (PFS) and overall survival (OS) according to COO classification algorithms.
| PFS | OS | |||
|---|---|---|---|---|
| RR (95% CI) | p | RR (95% CI) | p | |
| IPI score ‡ | 2.3 (1.5-3.6) | <0.001 | 2.49 (1.5-4.0) | <0.001 |
| Choi classification | 1.7 (1.1-2.7) | 0.016 | 1.7 (1.1-2.8) | 0.027 |
| IPI score ‡ | 2.2 (1.4-3.4) | <0.001 | 2.3 (1.4-3.7) | 0.001 |
| Hans classification | 1.7 (1.1-2.8) | 0.015 | 2.0 (1.2-3.4) | 0.007 |
| IPI score ‡ | 2.2 (1.4-3.4) | <0.001 | 2.4 (1.5-4.0) | <0.0001 |
| Visco-Young classification | 2.1 (1.3-3.5) | 0.003 | 2.1(1.2-3.6) | 0.006 |
Abbreviations: IPI, International Prognostic Index;
‡
The IPI score ranges from 0 to 5, with 0 indicating the absence of prognostic factors, and 5 indicating the presence of all prognostic factors. The IPI score was stratified by the proposed RIPI score.