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. 2016 Feb 27;7(14):18183–18203. doi: 10.18632/oncotarget.7784

Table 5. Histoclinical correlations of breast cancers according to galectins localization in cancer cells.

Characteristics Gal-1 % (n) Gal-2 % (n) Gal-3 % (n) Gal-8 % (n) Gal-9 % (n)
C C/N C M C C/N C C/N C C/N
Age, yr
 ≤ 45 14 (12) 9 (8) 9 (13) 10 (14) 3 (4) 17 (23) 10 (14) 11 (15) 5 (4) 14 (11)
 > 45 41 (35) 36 (31) 31 (43) 50 (71) 11 (15) 69 (96) 27 (37) 52 (70) 27 (22) 54 (44)
Tumor volume P = 0.002
 ≤ 10 cm3 33 (27) 21 (17) 24 (32) 31 (40) 8 (10) 51 (65) 16 (20) 44 (55) 14 (11) 41 (32)
 > 10 cm3 24 (19) 22 (18) 14 (19) 31(40) 7 (9) 34 (43) 22 (28) 18 (23) 17 (13) 28 (22)
Lymph node metastasis P = 0.043
 Negative 37 (32) 30 (26) 25 (34) 42 (59) 6 (8) 58 (79) 22 (29) 42 (56) 21 (17) 41 (33)
 Positive 18 (15) 15 (13) 16 (22) 17 (24) 8 (11) 28 (39) 16 (22) 20 (27) 11 (9) 27 (22)
SBR-EE Grade P < 0.0001 P = 0.024
 I (low) 6 (5) 4 (3) 12 (15) 2 (3) 1 (1) 21 (27) 2 (3) 15 (18) 1 (1) 15 (11)
 III (high) 46 (37) 44 (35) 28 (36) 58 (76) 14 (18) 64 (84) 35 (44) 48 (60) 30 (22) 54 (40)
Molecular subtypes P = 0.019 P < 0.0001 P < 0.0001
 Triple negative 22 (19) 33 (28) 7 (10) 37 (52) 7 (10) 33 (46) 24 (33) 14 (19) 17 (14) 23 (19)
 HER-2 positive 9 (8) 6 (5) 11 (15) 8 (11) 4 (5) 16 (23) 6 (8) 14 (19) 6 (5) 12 (10)
 Luminal A 22 (19) 6 (5) 20 (29) 14 (20) 3 (4) 33 (46) 7 (10) 31 (42) 9 (7) 32 (26)
 Luminal B 1 (1) 1 (1) 2 (3) 1 (2) 0 (0) 4 (5) 0 (0) 4 (5) 0 (0) 0 (0)
ER expression P = 0.007 P = 0.007 P = 0.0003
 Neg/Low 33 (28) 40 (34) 21 (30) 45 (64) 11 (15) 55 (77) 30 (41) 30 (41) 23 (19) 38 (31)
 High 22 (19) 6 (5) 19 (27) 15 (21) 3 (4) 31 (43) 7 (10) 33 (44) 9 (7) 30 (24)
PR expression P = 0.042
 Neg/Low 50 (43) 42 (36) 32 (45) 55 (78) 12 (17) 73 (102) 35 (47) 52 (71) 28 (23) 54 (44)
 High 5 (4) 3 (3) 8 (12) 5 (7) 1 (2) 13 (18) 3 (4) 10 (14) 4 (3) 14 (11)
HER-2 expression P = 0.023
 Neg/Low 43 (36) 39 (33) 27 (38) 51 (72) 10 (14) 66 (91) 31 (42) 45 (60) 26 (21) 56 (45)
 High 11 (9) 7 (6) 13 (18) 9 (13) 4 (5) 20 (28) 6 (8) 18 (24) 6 (5) 12 (10)
EGFR expression P = 0.008 P = 0.044
 Neg/Low 49 (42) 28 (24) 35 (49) 46 (65) 12 (16) 66 (90) 26 (35) 54 (72) 26 (21) 53 (42)
 High 6 (5) 17 (14) 6 (8) 13 (19) 2 (3) 20 (28) 11 (15) 9 (12) 6 (5) 15 (12)
Ki-67 expression P = 0.039 P = 0.002
 Neg/Low 33 (28) 19 (16) 27 (38) 29 (41) 8 (11) 54 (74) 15 (20) 42 (56) 16 (13) 41 (33)
 High 21 (18) 26 (22) 13 (19) 31 (44) 6 (8) 33 (45) 23 (31) 20 (27) 16 (13) 27 (22)

Fisher's exact test and chi-square test.