Table 7. Histoclinical correlations of breast cancers according to galectins expression in cancer-associated stroma.
| Characteristics | Gal-1 / Gal-3 / Gal-9 stromal expression | P | |
|---|---|---|---|
| Negative n = 104 | Triple positive n = 22 | ||
| Age, yr | 0.562 | ||
| ≤ 45 | 18% (22) | 2% (3) | |
| > 45 | 65% (81) | 15% (19) | |
| Tumor volume | 0.466 | ||
| ≤ 10 cm3 | 48% (55) | 9% (10) | |
| > 10 cm3 | 34% (39) | 10% (11) | |
| Lymph node metastasis | 1.000 | ||
| Negative | 52% (63) | 12% (14) | |
| Positive | 30% (36) | 7% (8) | |
| SBR-EE grade | 0.003 | ||
| I (low) | 24% (28) | 0% (0) | |
| III (high) | 58% (67) | 18% (21) | |
| Molecular subtype | < 0.0001 | ||
| Triple negative | 23% (29) | 13% (17) | |
| HER-2 positive | 12% (15) | 4% (5) | |
| Luminal A | 42% (53) | 0% (0) | |
| Luminal B (HER-2+) | 5% (7) | 0% (0) | |
| ER expression | < 0.0001 | ||
| Neg/Low | 41% (51) | 17% (22) | |
| High | 42% (53) | 0% (0) | |
| PR expression | 0.023 | ||
| Neg/Low | 66% (83) | 17% (22) | |
| High | 17% (21) | 0% (0) | |
| HER-2 expression | 1.000 | ||
| Neg/Low | 64% (80) | 14% (17) | |
| High | 18% (22) | 4% (5) | |
| EGFR expression | 0.0003 | ||
| Neg/Low | 72% (89) | 9% (11) | |
| High | 10% (13) | 9% (11) | |
| Ki-67 expression | 0.0005 | ||
| Neg/Low | 57% (71) | 5% (6) | |
| High | 26% (32) | 13% (16) | |
| p53 expression | 0.003 | ||
| Neg/Low | 65% (81) | 8% (10) | |
| High | 18% (22) | 10% (12) | |
Fisher's exact test and chi-square test.