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. 2016 Feb 22;7(14):18247–18261. doi: 10.18632/oncotarget.7570

Figure 5. miR-206 inhibitors increased the EMT, migration and invasion of cells.

Figure 5

A, B. The expression levels of p-c-Met, c-Met, p-Akt, Akt, p-mTOR, mTOR in A549 cells and 95D cells detected by western blots. miR-206 inhibitors significantly increased the expression of these proteins (except mTOR in A549 cells) compared with the negative control (NC). PI3k inhibitor LY294002 decreased the expression levels of all these proteins except Met and mTOR. C, D. LY294002 inhibited miR-206 inhibitor-induced EMT, migration and invasion both in A549 and 95D cells. ** P<0.01 vs its control as indicated in Figure. NC: Negative control; IN: miR-206 inhibitors; LY: LY294002.