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| Toxicity, maximum grade | grade 0 | grade 1 | grade 2 | grade 3 |
|---|---|---|---|---|
| QT prolongation | 21 | 1 | 2 | 1 |
| Abdominal pain | 22 | 3 | ||
| Chromaturia | 22 | 3 | ||
| Increased ALT | 22 | 3 | ||
| Increased AST | 23 | 2 | ||
| Leukopenia | 23 | 1 | 1 | |
| Lymphocytopenia | 23 | 1 | 1 | |
| Anemia | 24 | 1 | ||
| Neutropenia | 24 | 1 | ||
| Thrombocytopenia | 24 | 1 | ||
| Diarrhea | 24 | 1 | ||
| Insomnia | 24 | 1 | ||
| Fatigue | 24 | 1 | ||
| Nausea | 24 | 1 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase.
