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. 2016 Feb 23;7(14):18594–18604. doi: 10.18632/oncotarget.7617

Figure 2. miR-342 overexpression activates the intrinsic pathway of apoptosis in HCC1937 cells.

Figure 2

HCC1937 cells transfected with pre-miR-342 or with pre-miR-negative control were collected 24 and 48 hours after transfection. A. Representative flow cytometric detection of cells containing active caspase-3 from three independent experiments. B. Caspase-3 catalytic activity, based on hydrolysis of a specific fluorogenic substrate. Data are given as relative fluorescence units (r.f.u.) and represent mean ± SD from three independent determinations. *P<0.05 and **P<0.01 vs scramble.