Table 1. Expression ofPARP6 and Survivin and its correlation with Clinico-pathological features in CRC.
Clinico-pathological features | PARP6 expression | Survivin expression | ||||
---|---|---|---|---|---|---|
Low | High | p-value | Low | High | p-value | |
Normal colonic mucosa | 20 | 0 | 0 | 20 | ||
Colorectal cancer | 122 | 116 | 151 | 87 | ||
Age (years) | ||||||
≥50 | 110 | 111 | 142 | 79 | ||
<50 | 12 | 5 | 9 | 8 | ||
Sex | ||||||
Male | 70 | 70 | 94 | 46 | ||
Female | 52 | 46 | 57 | 41 | ||
Tumor size (mm) | ||||||
≥50 | 51 | 48 | 60 | 39 | ||
<50 | 71 | 68 | 91 | 48 | ||
Histological differentiation | ||||||
Por/Muc | 42 | 6 | <0.01 | 21 | 27 | <0.01 |
W/M | 80 | 110 | 130 | 60 | ||
Lymph node metastasis | ||||||
Negative | 50 | 75 | <0.01 | 99 | 26 | <0.01 |
Positive | 72 | 41 | 52 | 61 | ||
Lymphatic invasion | ||||||
Negative | 10 | 16 | 21 | 5 | ||
Positive | 112 | 100 | 130 | 82 | ||
Venous invasion | ||||||
Negative | 28 | 29 | 42 | 15 | ||
Positive | 94 | 87 | 109 | 72 | ||
Tumor stage | ||||||
BC | 82 | 106 | <0.01 | 135 | 53 | <0.01 |
D | 40 | 10 | 16 | 34 |