Table 3. Combination of PARP6 and Survivin expression and its correlation with Clinico-pathological features in CRC.
| PARP6 expression Survivin expression |
Low High |
High High |
Low Low |
High Low |
P-value |
|---|---|---|---|---|---|
| Total | 61 | 26 | 61 | 90 | |
| Age (years) | |||||
| ≥50 | 54 | 25 | 56 | 86 | |
| <50 | 7 | 1 | 5 | 4 | |
| Sex | |||||
| Male | 30 | 16 | 40 | 54 | |
| Female | 31 | 10 | 21 | 36 | |
| Tumor size (mm) | |||||
| ≥50 | 24 | 15 | 27 | 33 | |
| <50 | 37 | 11 | 34 | 58 | |
| Histological differentiation | |||||
| Por/Muc | 25 | 2 | 17 | 4 | <0.01 |
| W/M | 36 | 24 | 44 | 86 | |
| Lymph node metastasis | |||||
| Negative | 15 | 11 | 35 | 64 | <0.01 |
| Positive | 46 | 15 | 26 | 26 | |
| Lymphatic invasion | |||||
| Negative | 3 | 2 | 7 | 14 | |
| Positive | 58 | 24 | 54 | 76 | |
| Venous invasion | |||||
| Negative | 9 | 6 | 19 | 23 | |
| Positive | 52 | 20 | 42 | 67 | |
| Tumor stage | |||||
| BC | 34 | 19 | 48 | 87 | <0.01 |
| D | 27 | 7 | 13 | 3 |