Table 4. Stratified analyses for MEG3 rs7158663 genotypes in cases and controls.
| Variable | GG | GA/AA | OR (95%CI)a | Pa |
|---|---|---|---|---|
| N (case/control) | N (case/control) | |||
| Age (y), median | ||||
| ≤60 | 104/158 | 124/111 | 1.71 (1.20-2.44) | 0.003 |
| >60 | 160/140 | 128/108 | 1.04 (0.74-1.46) | 0.844 |
| Gender | ||||
| Male | 167/177 | 152/142 | 1.15 (0.84-1.57) | 0.396 |
| Female | 97/121 | 100/77 | 1.62 (0.98-2.34) | 0.076 |
| Smoking status | ||||
| Non-smokers | 168/207 | 178/155 | 1.42 (0.96-1.87) | 0.062 |
| Smokers | 96/91 | 74/64 | 1.10 (0.70-1.71) | 0.679 |
| Family history of cancer | ||||
| No | 204/268 | 200/210 | 1.25 (0.96-1.63) | 0.099 |
| Yes | 60/30 | 52/9 | 2.98 (1.28-6.92) | 0.011 |
a
Adjusted for age, sex, and smoking status.