Table 1. Patient and Tumor Characteristics.
| Variables | No. of patients (%) |
|---|---|
| Number of patients | 36 (100) |
| Age, yrs | |
| Median (range) | 42.5 (20-63) |
| <40 | 14 (38.9) |
| ≥40 | 22 (61.1) |
| Sex | |
| Male | 19 (52.8) |
| Female | 17 (47.2) |
| KPS at recurrence | |
| Median (range) | 60 (30-100) |
| <40 | 6 (16.7) |
| ≥40, <70 | 13 (36.1) |
| ≥70 | 17 (47.2) |
| Initial WHO grade | |
| I/II | 17 (47.2) |
| III | 5 (22.2) |
| IV | 14 (38.9) |
| WHO grade at recurrence | |
| I/II | 7 (19.4) |
| III | 8 (13.8) |
| IV | 21 (58.3) |
| MGMT methylation status at recurrence | |
| Methylated | 8 (22.2) |
| Unmethylated | 7 (19.4) |
| Unknown | 21 (58.3) |
| Salvage surgery at recurrence before re-irradiation | |
| Yes | |
| Gross total | 8 (22.2) |
| Subtotal | 19 (52.8) |
| No | |
| Biopsy | 1 (2.8) |
| Radiological diagnosis | 8 (22.2) |
KPS, Karnofsky performance status; WHO, World Health Organization; MGMT, O6-methylguanine-DNA methyltransferase.