Table 4. Characteristics of Patients Who Showed Suspicious MRI Findings of Radiation Necrosis after Re-Irradiation.
| Patient | Prior RT dose, Gy | Re-RT dose, Gy | Cumulative RT dose, Gy | Cumulative BED (α/β=2 Gy), Gy | Interval between RT, months | Time after re-RT, months | Treatment modality with re-RT after recurrence |
|---|---|---|---|---|---|---|---|
| 1 | 64.0 | 41.4 | 105.4 | 232.5 | 32 | 8 | re-Op+TMZ #9+re-RT |
| 2 | 59.4 | 59.4 | 118.8 | 225.7 | 173 | 7 | Re-RT+TMZ #6 |
| 3 | 50.4 | 45.0 | 95.4 | 181.3 | 19 | 3 | TMZ #6+re-RT |
| 4 | 59.4 | 50.0 | 109.4 | 225.4 | 33 | 7 | re-Op+re-RT |
| 5 | 48.6 | 60.0 | 108.6 | 212.3 | 20 | 4 | re-Op+re-RT+TMZ #5 |
| Median | 59.4 | 50.0 | 108.6 | 225.4 | 32 | 7 |
RT, radiation therapy; BED, biological equivalent dose; re-RT, re-irradiation; re-Op, re-operation; TMZ, temozolomide.