Table 3. Diagnostic tools of EGFR mutations and association with pathologic subtypes.
| Pathologic types | Cytology (n = 66) | Biopsy (n = 269) | Resection (n = 64) | Total (n = 399) | P value |
|---|---|---|---|---|---|
| Adeno | 59 | 171 | 51 | 281 (70.42) | |
| SqCC | 5 | 57 | 7 | 69 (17.29) | |
| Large cell carcinoma | 12 | 3 | 15 (3.75) | ||
| NSCLC | 1 | 6 | 7 (1.75) | ||
| SCLC | 1 | 11 | 12 (3.07) | ||
| Double primary (adeno + SqCC) | 2 | 1 | 3(0.75) | ||
| Pleomorphic carcinoma | 2 | 2 (0.50) | |||
| Metastatic carcinoma | 5 | 1 | 6 (1.50) | ||
| Clear cell carcinoma | 1 | 1 (0.25) | |||
| Malignant melanoma | 1 | 1 (0.25) | |||
| Mucoepidermoid carcinoma | 1 | 1 | 2 (0.50) | ||
| Adenocarcinoma | 59 (89.39) | 173 (64.31) | 52 (81.25) | 281 (70.42) | |
| Non-adenocarcinoma | 7 (10.61) | 96 (35.69) | 12 (18.75) | 118 (29.58) |