Table 4. Association between the outcome of eradication therapy and risk factors evaluated using logistic regression model.
| Variables | Eradication success rates No. (%) / Total | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
| Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value | |||
| Age in years | < 30 | 105 (72.92) / 144 | Reference | 0.002 | Reference | 0.009 |
| 30-39 | 251 (77.95) / 322 | 1.313 (0.835-2.064) | 1.337 (0.792-2.257) | |||
| 40-49 | 511 (76.73) / 666 | 1.224 (0.813-1.843) | 1.236 (0.764-2.000) | |||
| 50-59 | 917 (73.54) / 1,247 | 1.032 (0.700-1.522) | 0.995 (0.626-1.581) | |||
| 60-69 | 625 (70.7) / 884 | 0.896 (0.604-1.331) | 0.854 (0.531-1.373) | |||
| ≥ 70 | 292 (66.82) / 437 | 0.748 (0.492-1.136) | 0.753 (0.456-1.243) | |||
| Sex | Male | 1,643 (73.58) / 2,233 | Reference | 0.329 | NA | |
| Female | 1,058 (72.12) / 1467 | 0.929 (0.801-1.077) | NA | |||
| Residence | Seoul | 592 (73.18) / 809 | Reference | < 0.001 | Reference | < 0.001 |
| Gyeonggi | 496 (71.68) / 692 | 0.928 (0.739-1.164) | 0.859 (0.660-1.116) | |||
| Gangwon | 68 (73.12) / 93 | 0.997 (0.614-1.618) | 1.015 (0.560-1.841) | |||
| Chungcheong | 187 (60.32) / 310 | 0.557 (0.423-0.734) | 0.570 (0.413-0.786) | |||
| Gyeongsang | 884 (76.08) / 1,162 | 1.166 (0.949-1.432) | 1.128 (0.882-1.443) | |||
| Jeolla | 201 (72.83) / 276 | 0.982 (0.722-1.336) | 1.000 (0.712-1.405) | |||
| Jeju | 273 (76.26) / 358 | 1.177 (0.882-1.572) | 1.294 (0.948-1.766) | |||
| Current smoking | No | 1,486 (72.67) / 2,045 | Reference | 0.794 | NA | |
| Yes | 568 (71.45) / 795 | 0.941 (0.785-1.129) | NA | |||
| NA | 135 (72.97) / 185 | 1.016 (0.724-1.425) | NA | |||
| Alcohol consumption | No | 1,165 (71.17) / 1,637 | Reference | 0.264 | NA | |
| Yes | 894 (73.95) / 1,209 | 1.150 (0.973-1.359) | NA | |||
| NA | 129 (72.07) / 179 | 1.045 (0.741-1.474) | NA | |||
| Medication | No | 1,285 (73.05) / 1,759 | Reference | 0.022 | Reference | 0.012 |
| Yes | 781 (70.11) / 1,114 | 0.865 (0.733-1.021) | 0.947 (0.788-1.137) | |||
| NA | 85 (81.73) / 104 | 1.650 (0.993-2.744) | 2.500 (1.328-4.708) | |||
| Previous gastrointestinal disorder | No | 1,697 (73.30) / 2,315 | Reference | 0.019 | Reference | 0.038 |
| Yes | 382 (67.37) / 567 | 0.752 (0.617-0.917) | 0.816 (0.659-1.012) | |||
| NA | 83 (72.81) / 114 | 0.975 (0.639-1.488) | 0.595 (0.351-1.011) | |||
| Comorbidity | No | 1,289 (73.95) / 1,743 | Reference | 0.021 | NA | |
| Yes | 808 (69.54) / 1,162 | 0.804 (0.682-0.948) | NA | |||
| NA | 61 (77.22) / 79 | 1.194 (0.698-2.041) | NA | |||
| Previous H. pylori eradication | No | 2,581 (73.85) / 3,495 | Reference | < 0.001 | Reference | < 0.001 |
| Yes (within 1 yr) | 33 (55.0) / 60 | 0.433 (0.259-0.723) | 0.364 (0.207-0.640) | |||
| Yes (before 1 yr) | 87 (60.0)/145 | 0.531 (0.378-0.746) | 0.627 (0.425-0.925) | |||
| Duration in days | 7 | 2,435 (73.56) / 3,310 | Reference | < 0.001 | Reference | 0.019 |
| 14 | 216 (72.24) / 299 | 0.935 (0.718-1.218) | 0.918 (0.651-1.295) | |||
| Other | 50 (54.95) / 91 | 0.438 (0.288-0.667) | 0.520 (0.329-0.821) | |||
| Compliance | ≥ 80% | 2,653 (73.53) / 3,608 | Reference | < 0.001 | Reference | < 0.001 |
| < 80% | 22 (52.38) / 42 | 0.396 (0.215-0.729) | 0.375 (0.196-0.717) | |||
| NA | 25 (51.02) / 49 | 0.375 (0.213-0.660) | 0.390 (0.189-0.805) | |||
| Complication | No | 2,175 (73.31) / 2,967 | Reference | 0.626 | NA | |
| Yes | 437 (71.41) / 612 | 0.909 (0.749-1.103) | NA | |||
| NA | 88 (73.33) / 120 | 1.001 (0.663-1.513) | NA | |||
NA, not applicable.