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. 2016 Jun 11;6(4):319–328. doi: 10.1016/j.apsb.2016.05.010

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© 2016 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 9 — The histopathological examination of the major organs (lung and liver) 3 days post-treatment. Both DPD-L[D] and mPEG-L[D] groups received a single dose of daptomycin (25 mg/kg). Lung (H&E, 400×): () indicates alveolar atrophy or not expansion and alveolar wall thickening; () indicates neutrophils; () indicates eosinophils; () indicates dust cells. Liver (H&E 400×): () indicates cell granular degeneration and edema; () indicates Kupffer cells; () indicates infiltration of inflammatory cells including lymphocytes and neutrophils.

The histopathological examination of the major organs (lung and liver) 3 days post-treatment. Both DPD-L[D] and mPEG-L[D] groups received a single dose of daptomycin (25 mg/kg). Lung (H&E, 400×): () indicates alveolar atrophy or not expansion and alveolar wall thickening; () indicates neutrophils; () indicates eosinophils; () indicates dust cells. Liver (H&E 400×): () indicates cell granular degeneration and edema; () indicates Kupffer cells; () indicates infiltration of inflammatory cells including lymphocytes and neutrophils.