Figure 2.

Effect of Nepeta binaludensis on melanin content in B16F10 murine melanoma cells. B16F10 cells were incubated without (control) and with, 50 μg/ml of different N. binaludensis extracts for 48 hr. Melanin content was measured as described in ‘‘Materials and Methods.’’ As shown in the figure all extracts significantly decreased the melanin content in B16F10 cells. Results were expressed as percentages relative to control, and are presented as mean±SD of triplicate samples. Statistically significant difference between extract-treated cells and control ***(P<0.001)