Figure 4.

Effect of Nepeta binaludensis extracts on mushroom tyrosinase in B16F10 murine cells. Concentration 50 μg/ml of different N. binaludensis extracts and 2 mM of kojic acid were incubated with mushroom tyrosinase and L-DOPA at 37 °C. Mushroom tyrosinase activity was measured by the change in absorption at 475 nm. Results were expressed as percentages relative to control, and are presented as mean±SD of triplicate samples. Statistically significant difference between extract-treated cells and control *(P < 0.05), **(P < 0.01) and ***(P <0.001)