Figure 5.

Effect of Nepeta binaludensis extracts on cellular tyrosinase in B16F10 murine melanoma cells. After incubation of B16F10 melanoma cells with concentration 50 μg/ml of different N. binaludensis extracts for 48 hr, cellular tyrosinase activity was assessed as described in ‘‘Materials and Methods.’’ Results were expressed as percentages relative to control, and are presented as mean±SD of triplicate samples. Statistically significant difference between extract-treated cells and control **(P<0.01) and ***(P<0.001)