Table 1.
Morphology parameters of neuromuscular junction following lengthening contractions in mdx mice
| Mdx | Mdx + 9LC | C57 | C57 + 9LC | |
|---|---|---|---|---|
| Total NMJ area (μm2) | 2067.6 ± 145.7 | 1678.9 ± 83.0a | 1025.2 ± 69.0 | 1065.8 ± 44.3 |
| AChR area/NMJ (μm2) | 1005.2 ± 68.7 | 775.3 ± 30.3a | 512.6 ± 29.3 | 590.1 ± 33.0 |
| Complexity within NMJ (%) | 47.6 ± 2.2 | 48.7 ± 1.3 | 50.7 ± 1.7 | 56.0 ± 2.3 |
| AChR fragment number | 31.3 ± 2.7 | 29.1 ± 1.7 | 3.1 ± 0.7 | 3.5 ± 0.4 |
| AChR fragment area (μm2) | 75.6 ± 29.1 | 34.7 ± 4.3 | 276.6 ± 60.7 | 260.5 ± 34.7 |
n > 30 (C57) or >60 (mdx) per group (from 3 C57 mice and 4 mdx mice)
NMJ neuromuscular junction, AChR acetylcholine receptor, Mdx or C57 before nine lengthening contractions, Mdx + 9LC after nine lengthening contractions, C57 + 9LC after nine lengthening contractions
aSignificantly different from before nine lengthening contractions (p < 0.05)