Table 3.
Characteristics of currently alive HCV testers by HCV status and birth cohort, Canada, BC-HTC, 1990-2013
| HCV Positive | HCV Negative | |||||||
|---|---|---|---|---|---|---|---|---|
| <1945 | 1945-1964 | 1965-1974 | ≥1975 | <1945 | 1945-1964 | 1965-1974 | ≥1975 | |
| N = 3168 | N = 33946 | N = 11883 | N = 6784 | N = 95848 | N = 310845 | N = 209956 | N = 371732 | |
| N (%) | N (%) | N(%) | N (%) | N (%) | N(%) | N (%) | N (%) | |
| Age at baselinea | ||||||||
| < 15 | 0 | 0 | 0 | 438 (6.5) | 0 | 0 | 0 | 20289 (5.5) |
| 15-24 | 0 | 0 | 857 (7.2) | 2925 (43.1) | 0 | 0 | 3591 (1.7) | 141735 (38.1) |
| 25-34 | 0 | 2764 (8.1) | 6688 (56.3) | 3166 (46.7) | 0 | 6369 (2.1) | 66420 (31.6) | 186558 (50.2) |
| 35-44 | 0 | 14198 (41.8) | 4014 (33.8) | 255 (3.8) | 0 | 73286 (23.6) | 124190 (59.2) | 23150 (6.2) |
| 45-54 | 425 (13.4) | 13116 (38.6) | 324 (2.7) | 0 | 3166 (3.3) | 144213 (46.4) | 15755 (7.5) | 0 |
| ≥ 55 | 2743 (86.6) | 3868 (11.4) | 0 | 0 | 92682 (96.7) | 86977 (28.0) | 0 | 0 |
| Median [IQR] | 63 [58-70] | 45 [39-50] | 32 [28-37] | 25 [21–29] | 69 [63-75] | 50 [44-55] | 37 [33-41] | 26 [21–30] |
| Age at 1st test | ||||||||
| < 15 | 0 | 0 | 0 | 605 (8.9) | 0 | 0 | 0 | 25860 (7) |
| 15-24 | 0 | 0 | 1205 (10.1) | 3830 (56.5) | 0 | 0 | 7867 (3.8) | 181880 (48.9) |
| 25-34 | 0 | 3074 (9.1) | 7174 (60.4) | 2182 (32.2) | 0 | 12382 (4.0) | 96703 (46.1) | 151971 (40.9) |
| 35-44 | 0 | 14485 (42.7) | 3255 (27.4) | 167 (2.5) | 0 | 99462 (32.0) | 96915 (46.2) | 12021 (3.2) |
| 45-54 | 436 (13.8) | 12742 (37.5) | 249 (2.1) | 0 | 5217 (5.4) | 134000 (43.1) | 8471 (4.0) | 0 |
| ≥ 55 | 2732 (86.2) | 3645 (10.7) | 0 | 0 | 90631 (94.6) | 65001 (20.9) | 0 | 0 |
| Median [IQR] | 63 [58-69] | 44 [39-50] | 31 [27-36] | 22 [18–27] | 67 [61-73] | 48 [42-53] | 35 [30-39] | 24 [20–28] |
| Sex | ||||||||
| Female | 1354 (42.7) | 10946 (32.3) | 4288 (36.1) | 3261 (48.1) | 51063 (53.3) | 164778 (53.0) | 116339 (55.4) | 219772 (59.1) |
| Male | 1809 (57.1) | 23000 (67.8) | 7594 (63.9) | 3523 (51.9) | 44657 (46.6) | 146061 (47.0) | 93615 (44.6) | 151954 (40.9) |
| Unknown | 5 (0.2) | 0 | 0 | 0 | 128 (0.1) | 6 (0.0) | 2 (0.0) | 6 (0.0) |
| Year of diagnosis | ||||||||
| 1990-1994 | 340 (10.7) | 2938 (8.7) | 690 (5.8) | 99 (1.5) | 822 (0.9) | 1858 (0.6) | 889 (0.4) | 344 (0.1) |
| 1995-1999 | 1186 (37.4) | 12980 (38.2) | 3992 (33.6) | 857 (12.6) | 21815 (22.8) | 48746 (15.7) | 21003 (10.0) | 13299 (3.6) |
| 2000-2004 | 703 (22.2) | 8333 (24.6) | 3163 (26.6) | 1650 (24.3) | 19159 (20.0) | 68035 (21.9) | 43673 (20.8) | 42021 (11.3) |
| 2005-2009 | 555 (17.5) | 6004 (17.7) | 2588 (21.8) | 2257 (33.3) | 22709 (23.7) | 81513 (26.2) | 63756 (30.4) | 104908 (28.2) |
| 2010-2013 | 384 (12.1) | 3691 (10.9) | 1450 (12.2) | 1921 (28.3) | 31343 (32.7) | 110693 (35.6) | 80635 (38.4) | 211160 (56.8) |
| HIV/AIDS at baseline | ||||||||
| No/Unknown | 3149 (99.4) | 33150 (97.7) | 11364 (95.6) | 6562 (96.7) | 95664 (99.8) | 308950 (99.4) | 208736 (99.4) | 370832 (99.8) |
| Yes | 19 (0.6) | 796 (2.3) | 519 (4.4) | 222 (3.3) | 184 (0.2) | 1895 (0.6) | 1220 (0.6) | 900 (0.2) |
| HIV/AIDS co-infection (ever) | ||||||||
| No/Unknown | 3135 (99.0) | 32345 (95.3) | 10810 (91.0) | 6335 (93.4) | 95640 (99.8) | 308728 (99.3) | 208587 (99.4) | 370739 (99.7) |
| Yes | 33 (1.0) | 1601 (4.7) | 1073 (9.0) | 449 (6.6) | 208 (0.2) | 2117 (0.7) | 1369 (0.7) | 993 (0.3) |
| HBV at baseline | ||||||||
| No/Unknown | 3130 (98.8) | 33529 (98.8) | 11686 (98.3) | 6729 (99.2) | 94660 (98.8) | 304567 (98.0) | 206304 (98.3) | 368692 (99.2) |
| Yes | 38 (1.2) | 417 (1.2) | 197 (1.7) | 55 (0.8) | 1188 (1.2) | 6278 (2.0) | 3652 (1.7) | 3040 (0.8) |
| HBV co-infection (ever) | ||||||||
| No/Unknown | 3075 (97.1) | 32643 (96.2) | 11330 (95.4) | 6658 (98.1) | 94059 (98.1) | 302130 (97.2) | 204856 (97.6) | 367414 (98.8) |
| Yes | 93 (2.9) | 1303 (3.8) | 553 (4.7) | 126 (1.9) | 1789 (1.9) | 8715 (2.8) | 5100 (2.4) | 4318 (1.2) |
| Active TB at baseline | ||||||||
| No/Unknown | 3157 (99.7) | 33890 (99.8) | 11863 (99.8) | 6773 (99.8) | 95584 (99.7) | 310307 (99.8) | 209650 (99.9) | 371368 (99.9) |
| Yes | 11 (0.4) | 56 (0.2) | 20 (0.2) | 11 (0.2) | 264 (0.3) | 538 (0.2) | 306 (0.2) | 364 (0.1) |
| Active TB co-infection (ever) | ||||||||
| No/Unknown | 3149 (99.4) | 33783 (99.5) | 11808 (99.4) | 6752 (99.5) | 95494 (99.6) | 310145 (99.8) | 209558 (99.8) | 371276 (99.9) |
| Yes | 19 (0.6) | 163 (0.5) | 75 (0.6) | 32 (0.5) | 354 (0.4) | 700 (0.2) | 398 (0.2) | 456 (0.1) |
| Material deprivation quintile at baseline | ||||||||
| Unknown | 106 (3.4) | 1298 (3.8) | 618 (5.2) | 469 (6.9) | 1199 (1.3) | 3720 (1.2) | 2671 (1.3) | 7183 (1.9) |
| Q1 (most privileged) | 507 (16.0) | 4444 (13.1) | 1362 (11.5) | 830 (12.2) | 18845 (19.7) | 65327 (21.0) | 48322 (23.0) | 81513 (21.9) |
| Q2 | 513 (16.2) | 5404 (15.9) | 1636 (13.8) | 936 (13.8) | 18165 (19.0) | 60803 (19.6) | 39355 (18.7) | 69264 (18.6) |
| Q3 | 533 (16.8) | 6114 (18) | 1926 (16.2) | 1065 (15.7) | 19060 (19.9) | 61814 (19.9) | 40022 (19.1) | 71369 (19.2) |
| Q4 | 660 (20.8) | 7365 (21.7) | 2691 (22.7) | 1514 (22.3) | 20032 (20.9) | 61824 (19.9) | 40792 (19.4) | 74468 (20.0) |
| Q5 (most deprived) | 849 (26.8) | 9321 (27.5) | 3650 (30.7) | 1970 (29.0) | 18547 (19.4) | 57357 (18.5) | 38794 (18.5) | 67935 (18.3) |
| Social deprivation quintile at baseline | ||||||||
| Unknown | 106 (3.4) | 1298 (3.8) | 618 (5.2) | 469 (6.9) | 1199 (1.3) | 3720 (1.2) | 2671 (1.3) | 7183 (1.9) |
| Q1 (most privileged) | 557 (17.6) | 3477 (10.2) | 1081 (9.1) | 741 (10.9) | 17348 (18.1) | 57695 (18.6) | 36550 (17.4) | 68621 (18.5) |
| Q2 | 513 (16.2) | 4335 (12.8) | 1238 (10.4) | 794 (11.7) | 17802 (18.6) | 56839 (18.3) | 36109 (17.2) | 64348 (17.3) |
| Q3 | 516 (16.3) | 5802 (17.1) | 1790 (15.1) | 989 (14.6) | 17342 (18.1) | 56864 (18.3) | 36204 (17.2) | 65305 (17.6) |
| Q4 | 606 (19.1) | 7152 (21.1) | 2380 (20.0) | 1257 (18.5) | 19201 (20.0) | 62437 (20.1) | 42960 (20.5) | 76953 (20.7) |
| Q5 (most deprived) | 870 (27.5) | 11882 (35.0) | 4776 (40.2) | 2534 (37.4) | 22956 (24.0) | 73290 (23.6) | 55462 (26.4) | 89322 (24.0) |
| Mental illness at baselineb | ||||||||
| No/Unknown | 2768 (89.8) | 28051 (85.0) | 9468 (81.9) | 4942 (79.5) | 75892 (90.3) | 230429 (85.6) | 160387 (87.7) | 262690 (89.8) |
| Yes | 316 (10.2) | 4956 (15.0) | 2087 (18.1) | 1277 (20.5) | 8130 (9.7) | 38636 (14.4) | 22397 (12.3) | 29891 (10.2) |
| Mental illness 3yr pre- baselineb | ||||||||
| No/Unknown | 2908 (94.3) | 30114 (91.2) | 10261 (88.8) | 5478 (88.1) | 80387 (95.7) | 251001 (93.3) | 172141 (94.2) | 277513 (94.8) |
| Yes | 176 (5.7) | 2893 (8.8) | 1294 (11.2) | 741 (11.9) | 3635 (4.3) | 18064 (6.7) | 10643 (5.8) | 15068 (5.2) |
| Illicit drug use at baselineb | ||||||||
| No/Unknown | 2763 (89.6) | 22649 (68.6) | 6220 (53.8) | 3256 (52.4) | 81535 (97.0) | 249677 (92.8) | 167729 (91.8) | 271558 (92.8) |
| Yes | 321 (10.4) | 10358 (31.4) | 5335 (46.2) | 2963 (47.6) | 2487 (3.0) | 19388 (7.2) | 15055 (8.2) | 21023 (7.2) |
| Illicit drug use 3yr pre- baselineb | ||||||||
| No/Unknown | 2870 (93.1) | 25193 (76.3) | 7090 (61.4) | 3557 (57.2) | 83133 (98.9) | 259681 (96.5) | 174045 (95.2) | 278466 (95.2) |
| Yes | 214 (6.9) | 7814 (23.7) | 4465 (38.6) | 2662 (42.8) | 889 (1.1) | 9384 (3.5) | 8739 (4.8) | 14115 (4.8) |
| Problematic alcohol use at baselineb | ||||||||
| No/Unknown | 2724 (88.3) | 25720 (77.9) | 8780 (76.0) | 4933 (79.3) | 79838 (95.0) | 248826 (92.5) | 171200 (93.7) | 277407 (94.8) |
| Yes | 360 (11.7) | 7287 (22.1) | 2775 (24.0) | 1286 (20.7) | 4184 (5.0) | 20239 (7.5) | 11584 (6.3) | 15174 (5.2) |
| Problematic alcohol use 3yr pre-baselineb | ||||||||
| No/Unknown | 2870 (93.1) | 28620 (86.7) | 9874 (85.5) | 5421 (87.2) | 81897 (97.5) | 258911 (96.2) | 177020 (96.8) | 284664 (97.3) |
| Yes | 214 (6.9) | 4387 (13.3) | 1681 (14.5) | 798 (12.8) | 2125 (2.5) | 10154 (3.8) | 5764 (3.2) | 7917 (2.7) |
aBaseline is defined as date of diagnosis (i.e. first HCV positive test or case report) for HCV positive individuals, and date of last negative test result for HCV negative individuals
bMental health, drug misuse, alcohol misuse data was available up to 2012