Table 4.
Multivariable multinomial logistic regression models for factors associated with seroconversion and prevalent HCV infection in BC-HTC, Canada 1990-2012a, b
| Variables | Seroconverters | Prevalent HCV |
|---|---|---|
| ORs (95 % CI) | ORs (95 % CI) | |
| Sex | ||
| Female | 1.00 | 1.00 |
| Male | 1.25 (1.19-1.31) | 2.06 (2.02-2.10) |
| Birth year | ||
| < 1945 | 1.00 | 1.00 |
| 1945-1954 | 3.38 (2.78-4.11) | 3.79 (3.67-3.92) |
| 1955-1964 | 6.22 (5.19-7.44) | 3.23 (3.13-3.34) |
| 1965-1974 | 9.86 (8.26-11.78) | 1.64 (1.58-1.70) |
| 1975-1984 | 11.76 (9.83-14.07) | 0.70 (0.67-0.73) |
| ≥ 1985 | 6.53 (5.34-7.99) | 0.48 (0.44-0.51) |
| HIV infection at baselinec | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 7.92 (7.05-8.89) | 4.80 (4.47-5.15) |
| HBV at baselinec | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 2.33 (2.00-2.71) | 0.69 (0.63-0.75) |
| Active TB at baselinec | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 1.00 (0.62-1.62) | 1.01 (0.81-1.25) |
| Material deprivation quintile at baselinec | ||
| Unknown | 3.51 (2.96-4.17) | 5.38 (5.07-5.70) |
| Q1 (most privileged) | 1.00 | 1.00 |
| Q2 | 1.20 (1.06-1.31) | 1.22 (1.18-1.27) |
| Q3 | 1.24 (1.13-1.36) | 1.36 (1.32-1.41) |
| Q4 | 1.62 (1.48-1.76) | 1.60 (1.55-1.65) |
| Q5 (most deprived) | 1.99 (1.83-2.15) | 1.98 (1.92-2.04) |
| Mental illness at baselinec | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 1.18 (1.12-1.25) | 0.69 (0.67-0.72) |
| Illicit drugs use at baseline | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 21.00 (19.80-22.38) | 5.03 (4.91-5.16) |
| Problematic alcohol use at baseline | ||
| No/Unknown | 1.00 | 1.00 |
| Yes | 2.11 (2.00-2.23) | 1.67 (1.63-1.72) |
aAdjusted for health authority and year of diagnosis; bExcluding unknown gender and health authority. cBaseline is defined as time of diagnosis for HCV positive, and date of last negative for HCV negative