Fig 1. STEMI pathway. *At the time of publication of CG167, Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention (TA182) was referred to be updated. The updated technology appraisal guidance has since been published (TA317; www.nice.org.uk/guidance/ta317). LMWH = low molecular weight heparin; NICE = National Institute for Health and Care Excellence; PPCI = primary percutaneous coronary intervention; STEMI = ST-segment-elevation myocardial infarction; UFH = unfractionated heparin.