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. 2016 Jun 8;5(8):1079–1089. doi: 10.5966/sctm.2015-0263

Figure 3.

Figure 3.

The role of foreign body multinucleated giant cells (FBGCs) in the inflammatory responses to engineered cartilage in vivo. (A–D): Representative H&E staining images of engineered cartilage constructs after 2 weeks in vivo at low magnification and the white dotted lines depict the boundary of the implants. (E–H): Quantitative comparison of FBGCs from H&E stained images at high magnification after 2 weeks and 8 weeks post implantation among the groups of BMSCs, 1:1, chondrocytes, and PGA/PLA (I). ∗, p < .05 (statistically different from other groups). Scale bars = 50 μm (A–D) and 100 μm (E–H). Abbreviations: ACs, articular chondrocytes; BMSCs, bone marrow mesenchymal stem cells; PGA, polyglycolic acid; PLA, polylactic acid; w, weeks.