Skip to main content
. 2016 Jun 22;5(8):1067–1078. doi: 10.5966/sctm.2015-0281

Figure 6.

Figure 6.

Cardiomyocyte differentiation of CPC grafts in host ischemic heart. (A): Confocal micrographs of cardiac tissue sections from control-CPC (A1–A3) and APE1-CPC (A4–A6) mice labeled for cardiac α-SA expression on day 7 after injection. Middle: transplanted cells (red); right: cardiac α-SA (green); left: merged image of transplanted cells (red), cardiac α-SA (green), and cell nuclei stained with DAPI (blue). (B): Number of CPC grafts positive for cardiac α-SA in the total ischemic area and border and infarct areas. (C): Ratio of cardiac α-SA-positive CPC grafts in each area (n = 6 per group). Scale bar, 50 μm. ∗, p < .05. Abbreviations: APE1, apurinic/apyrimidinic endonuclease/redox factor 1; CPC, cardiac progenitor cell; Ct, control; DAPI, 4′,6-diamidino-2-phenylindole; SA, sarcomeric actinin.