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. 2016 May 31;5(8):991–1003. doi: 10.5966/sctm.2015-0295

Figure 5.

Figure 5.

Stromal cell infusion reduces the acute lesion volume. (A): In vivo very high-resolution ultrasound imaging in B-Mode (11 × 7 mm) was used to quantify the acute lesion volume. (B, C): Representative images of the C7 (35 g) SCI lesion (B) and quantified volumes (C) are shown over time. (D): HUCMCs as well as HBVPs reduced the SCI lesion volume at 1, 3, and 7 days. Data are expressed as mean ± SEM. (E): Representative images of the VHRUS scans and 3D lesion reconstructions are shown for all the experimental groups. One-way analysis of variance (Dunnett’s for temporal profiles, Tukey’s post hoc for cell comparison). ∗, p ≤ .05; ∗∗, p ≤ .01; ∗∗∗, p ≤ .001; ∗∗∗∗, p ≤ .0001. Abbreviations: 3D, three-dimensional; HBVPs, human brain vascular pericytes; HUCMCs, human umbilical cord matrix cells; SCI, spinal cord injury; VHRUS, very high-resolution ultrasound; Vol, volume.