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Study design and porcine model preparation of chronic myocardial ischemia. (A): Study design. (B): An ameroid constrictor was placed around the left circumflex artery (LCX) to create a porcine model of chronic myocardial ischemia. (C): Four weeks after the implantation of the ameroid constrictor, left coronary angiography images showed complete occlusion of the LCX. Abbreviations: LAD, left anterior descending artery; UC-MSCs, umbilical cord-derived mesenchymal stromal cells.
