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. 2016 Feb 18;10(4):297–312. doi: 10.1080/19336950.2016.1153203

Table 1.

Proteins identified in immunoprecipitated cerebellar iFGF14 complexes.

Identified Protein Gene Average number of unique peptides (total spectra) Average % amino acid sequence coverage
    WT Fgf14−/−  
Voltage-gated Na+ channel α subunit Nav1.2 Scn2a 58 (158) 0 27
Voltage-gated Na+ channel α subunit Nav1.1 Scn1a 35 (73) 0 24
Voltage-gated Na+ channel α subunit Nav1.6 Scn8a 23 (45) 0 17
FGF14 Fgf14 10 (26) 0 51
Calmodulin Calm 9 (33) 2 (3) 55
Voltage-gated Na+ channel β2 subunit Scn2b 9 (21) 0 35
Voltage-gated Na+ channel α subunit Nav1.4 Scn4a 2 (12) 0 3
Synaptotagmin-1 Syt1 2 (3) 0 16
Synaptotagmin-2 Syt2 15 (32) 2 (2) 57
Voltage-gated Na+ channel β1 subunit Scn1b 8 (17) 0 28
Ankyrin R Ank1 4 (4) 0 3
Ankyrin G Ank3 9 (10) 0 6
Inositol 1,4,5-trisphosphate receptor type 1 Itpr1 4 (4) 0 2
Voltage-dependent anion-selective channel protein 1 Vdac1 2 (2) 0 7
Vesicle-associated membrane protein-associated protein A Vapa 2 (4) 0 13
Voltage-gated Na+ channel β4 subunit Scn4b 2 (3) 0 7
Excitatory amino acid transporter 1 Slc1a3 5 (7) 2 (2) 14
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Atp2a2 2 (3) 0 3
Casein kinase II subunit β Csnk2b 1 (1) 0 5
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit β−1 Gnb1 1 (1) 0 4
Solute carrier family 12 member 5 Slc12a5 1 (1) 0 1
Protein-glutamine gamma-glutamyltransferase 2 Tgm2 1 (1) 0 3
Neurofascin Nfasc 1 (1) 0 1
14-3-3 protein theta Ywhaq 1 (1) 0 14
Synaptosomal-associated protein 25 Snap25 1 (1) 0 9

Note. The average number of exclusive unique peptides and total spectra as well as the average percent amino acid sequence coverage obtained for each protein (from a total of 4 runs in each condition) are presented. Rows in bold indicate voltage-gated Na+ (Nav) channel α subunits or previously identified Nav channel interacting proteins.