Fig 2. Support Structure Reduction.

(Left) Schematic of the standard-SNM with a 400 μm thick support structure that results in a longer diffusion path and decreased diffusive transport. The mass transfer coefficients for blood (k_b), membrane (k_m), support structure (k_s) and dialysate (k_d) are shown in the figure. (Right) Depicts the diffusive-SNM with a reduced support structure (100 μm) resulting in improved diffusive clearance due to the decreased resistance from the support structure. The mass transfer coefficients for k_d is rework to take into account the cavity (k_{d, cavity}) and the channel (k_{d, channel}).