Table 3. Molecular function terms (Gene ontology) overrepresented for UP- and DOWN-regulated genes from ovine peripheral blood mononuclear cells (PBMCs) after 2 weeks post infection with Fasciola hepatica.
GO molecular function | Fold Enrichment | P value | UP | DOWN |
---|---|---|---|---|
arachidonic acid binding | 69.38 | 3.40E-02 | S100A9, S100A8, ALOX5AP | |
RAGE receptor binding | 50.46 | 3.95E-03 | S100A9, S100A12, S100A8, S100A4 | |
cytokine receptor binding | 5.53 | 1.63E-02 | PF4V1, SMAD2, LRG1, CCL23, CCL2, TGFB1, EBI3, PYCARD, TFF2, ECM1 | PLCG1 |