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. 2016 Jul 20;11(7):e0159485. doi: 10.1371/journal.pone.0159485

Table 2. Differences in covariates between the cognitive impairment group and the normal cognition group.

Variables CI (n = 231) NC (n = 1568) P
Gender [n(%)] 0.300
Male 86(11.8) 640(88.2)
Female 145(13.5) 928(86.5)
Age [n(%)] <0.001
40–49 27(4.6) 557(95.4)
50–59 88(14.3) 527(85.7)
60–69 52(12.6) 362(87.4)
≥70 64(34.4) 122(65.6)
Edu years [Median(P25,P75), y] 5(0,8) 8(5,9) <0.001
Marital status [n(%)] <0.001
Married 195(11.9) 1446(88.1)
Others 36(22.8) 122(77.2)
DM [n(%)] 0.001
Y 44(20.0) 176(80.0)
N 187(11.8) 1392(88.2)
CHD [n(%)] 0.001
Y 13(28.9) 32(71.1)
N 218(12.4) 1536(87.6)
Dyslipidemia [n(%)] 0.121
Y 129(14.0) 790(86.0)
N 102(11.6) 778(88.4)
TIA [n(%)] 0.283
Y 2(6.5) 29(93.5)
N 229(13.0) 1539(87.0)
Family history of stroke [n(%)] 0.002
Y 28(7.9) 325(92.1)
N 203(14.0) 1243(86.0)
Family history of CHD [n(%)] <0.001
Y 5(4.3) 111(95.7)
N 225(13.4) 1451(86.6)
U 1(14.3) 6(85.7)
Family history of HP [n(%)] <0.001
Y 45(8.1) 512(91.9)
N 185(14.9) 1053(85.1)
U 1(25.0) 3(75.0)
Family history of DM [n(%)] 0.072
Y 16(11.0) 130(89.0)
N 214(13.0) 1431(87.0)
U 1(12.5) 7(87.5)
Tobacco use [n(%)] 0.640
Y 63(12.3) 451(87.7)
N 168(13.1) 1117(86.9)
Alcohol consumption [n(%)] 0.197
Y 26(10.3) 226(89.7)
N 205(13.3) 1342(86.7)
Lack of physical activity [n(%)] 0.020
Y 47(17.2) 227(82.8)
N 184(12.1) 1341(87.9)
Cardiac murmur [n(%)] 0.058
Y 8(26.7) 22(73.3)
N 222(12.7) 1532(87.3)
U 1(6.7) 14(93.3)
Arrhythmia [n(%)] 0.111
Y 9(20.9) 34(79.1)
N 222(12.7) 1527(87.3)
U 0(0.0) 7(100)
Antihypertensive drugs [n(%)] 0.108
Y 40(16.0) 210(84.0)
N 191(12.3) 1358(87.7)
WHR [Median(P25, P75)] 0.889(0.843,0.925) 0.879(0.842,0.916) 0.165
BMI [Mean(SD), kg/m2] 24.86(3.38) 25.37(3.18) 0.024
Pulse rate [Mean(SD)] 76.05(10.62) 75.22(8.52) 0.182
TC [Mean(SD), mmol/L] 5.19(1.06) 5.02(0.99) 0.017
TG [Median(P25,P75), mmol/L] 1.47(1.02,2.03) 1.43(1.03,2.00) 0.605
LDL [Mean(SD), mmol/L] 3.42(0.95) 3.30(0.89) 0.046
HDL [Mean(SD),mmol/L] 1.43(0.31) 1.40(0.31) 0.133
FBG [Median(P25,P75),mmol/L] 5.42(5.05,6.02) 5.40(5.07,5.81) 0.335

Edu, education; CI, cognitive impairment; NC, normal cognition; DM, diabetes mellitus; CHD, coronary heart disease; TIA, transient ischemic attack; HP, hypertension; WHR, waist-to-hip ratio; BMI, body mass index; TC, total cholesterol; TG, triglycerides; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FBG, fasting blood glucose.