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. 2016 Jul 20;11(7):e0159417. doi: 10.1371/journal.pone.0159417

Fig 1. Cytokines and chemokines in lung tissue after sham procedure or double hit (DH) in wild type (wt) mice (black bars) or in absence of C5 (C5-/-) mice (grey bars). Systemic effects of the absence of complement C5 in double hit (DH).

Fig 1

A. Increased IL-6 levels in lung tissue of wt and in C5-/- mice after DH compared to sham. B. Increased MCP-1 levels in lung tissue of wt and in C5-/- after DH compared to sham. C. Increased G-CSF levels in lung tissue of wt and in C5-/- mice after DH compared to sham. D. Increased KC levels in lung tissue of wt mice. E. Increased KC plasma concentration in wt mice after DH; decreased KC plasma concentrations after DH in C5-/- compared wt mice. F. Increased MCP-1 plasma concentrations in wt mice after DH, decrease of MCP-1 after DH in absence of C5. For each bar, n = 7 separate mice. * p<0.05, n.s. = not significant.