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| Parameters | Definition | Estimate | RSE (%) | IIV(CV%) |
|---|---|---|---|---|
| v0 (cm3) | Tumor size at time 0 | 0.0143 | 17 | 26.9 |
| kng (day−1) | Tumor growth rate | 0.282 | 6 | – |
| Tss (cm3) | Maximum of tumor size | 2.62 | 25 | – |
| kTM208 (day−1) | Antitumor effect of the inhibition | 0.0499 | 18 | – |
| k1 (day−1) | Transit rate constant | 0.141 | 15 | – |
| Residual error | ||||
| σ1 (Proportional) | CV% | 23.32 | 12 | – |
| σ2 (Additive) | SD (cm3) | 0.012 | 21 | – |
