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Schematic representation of class I; HDAC1, 2, 3 and 8, class IIa; HDAC4, 5, 7 and 9, class IIb; HDAC6 and 10 and class IV; HDAC11. HDAC enzymes with the structural and the functional domains included the capacity of the structurally diverse HDAC inhibitors to inhibit the activity of each HDAC classes or specific isoform HDACs are shown. Adapted from Bolden et al. (2006)
