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Carbapenem and nitrocefin hydrolysis kinetics of OXA-48
| Substrate | Km (μM) | kcat (s−1) | kcat/Km (μM−1 s−1) |
|---|---|---|---|
| Nitrocefin | 65.7 ± 18.9 | 314.7 ± 18.9 | 4.79 |
| Imipenem | 60.3 ± 12.4 | 1.5 ± 0.1 | 0.025 |
| Ertapenem | 123.7 ± 36.2 | 0.3 ± 0.02 | 0.002 |
Data represent the means of three independent experiments.
