Table 1. The clockwise (+)/counterclockwise (−) rotation of the transmembrane helices.

The average rotational degrees of TM1 and TM2 in each subunit were calculated over 10−100 ns MD simulations. Along the axis from extracellular to intracellular side (viewed from the outside to the inside membrane), the plus (+, in light grey) indicated a clockwise rotation of TM, while a minus (−, in dark grey) indicated a counterclockwise rotation. The magnitudes of the degrees of rotation are listed on Table S1.