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. 2016 Jun 19;6(10):1641–1650. doi: 10.7150/thno.14958

Figure 4.

Figure 4

A: 50-year-old patient (No. 1) with bilateral ER/PR-positive NST. Note the detection of a very small (3x3 mm) internal mammary lymph node (IMLN) with intensive 68Ga-RM2-uptake (SUVMAX 3.8). CT (left); 68Ga-RM2-PET (middle); fusion image (right); suspicious IMLN (lateral to internal mammary vessels) indicated by red arrows. B: 43-year-old patient (No. 15) with a ER/PR-positive NST of the left breast. Note the contralateral axillary lymph node metastasis with increased GRPR expression (verified by biopsy; SUVMAX 2.6). CT (left); 68Ga-RM2-PET (middle); fusion image (right); contralateral lymph node metastasis indicated by red arrows. C: 80-year-old patient (No. 14) with an ER/PR-positive NST of the right breast. CT did not show any noticeable bone alteration, while 68Ga-RM2-PET depicted intense focal gastrin-releasing peptide receptor expression in the right acetabulum (among other locations) highly suspicious of a bone metastasis (SUVMAX 14.3). CT (left); 68Ga-RM2-PET (middle); fusion image (right). Suspicious bone lesion indicated by red arrows. For abbreviations see text.