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Characterization of Gd(DTPA-CPT) nanoparticles. (a) 1H NMR spectra of CPT, DTPAA, and DTPA-CPT in DMSO-d6. (b) Representative TEM image of Gd(DTPA-CPT) nanoparticles. Scale bar, 0.2 µm. (c) Hydrodynamic diameter distribution of Gd(DTPA-CPT) nanoparticles in water. (d) Diffusion rate of free CPT, Gd(DTPA-CPT) nanoparticles and PEG-b-PCL nanoparticles determined by equilibrium dialysis.
