Table 2.
Summary of the results of the enrichment analysis using XPCLR scores as the baseline
| Population pair (Objective-Reference) |
GSEA: Daub et al. [19] (# of gene sets) |
GSEA: GOWINDA (# of gene sets) |
Total # of pathways for each population, and the in common pathways between the two GSEA approaches |
|---|---|---|---|
| CEU-YRI | 3 | 0 | 3 |
| YRI- CEU | 0 | 2 | 2 |
| YRI- CHB + JTP | 1 | 7 | 8 of which 1 in common (Cell surface interactions at the vascular wall) |
| CHB + JTP-YRI | 1 | 1 | 2 |
| CEU- CHB + JTP | 0 | 1 | 1 |
| CHB + JTP-CEU | 1 | 1 | 2 |
| Total # of pathways for each GSEA | 6 | 12 | 18 of which 1 in common (Cell surface interactions at the vascular wall) |
The population on the left is considered to be the objective one, while the one on the right the reference one under all circumstances. Threshold is set to <0.09