Table 3.

Univariate and multivariate Cox regression analyses LINC00261 for DFS of patients in the study cohort (n = 138)

Variables	DFS
	HR	95 % CI	P value
Univariate analysis
Age (<50 vs. >50 years)	0.874	0.537–1.424	0.589
Gender (male vs. female)	0.802	0.484–1.329	0.392
Location (distal vs. middle + proximal)	0.793	0.487–1.292	0.351
Tumor size (>5 vs. <5 cm)	1.336	1.041–1.714	0.023*
Histologic differentiation (well + moderately vs. poorly + undifferentiated)	1.626	0.966–2.738	0.068
Invasion depth (T1 + T2 vs. T3 + T4)	1.174	0.721–1.911	0.518
TNM stage (III + IV vs. I + II)	2.620	1.561–4.395	<0.001*
Lymphatic metastasis (no vs. yes)	0.749	0.583–0.963	0.024*
Regional lymph nodes (PN2 + PN3 vs. PN0 + PN1)	1.818	1.111–2.972	0.017*
Distant metastasis (no vs. yes)	0.654	0.482–0.888	0.007*
Expression of LINC00261 (high vs. low)	0.494	0.300–0.812	0.005*
Multivariate analysis
TNM stage (III + IV vs. I + II)	1.805	1.090–2.990	0.022*
Lymphatic metastasis (no vs. yes)	0.887	0.665–1.246	0.125
Regional lymph nodes (PN2 + PN3 vs. PN0 + PN1)	1.117	0.592–2.111	0.732
Tumor size (>5 vs. <5 cm)	1.086	0.835–1.433	0.510
Distant metastasis (no vs. yes)	0.584	0.294–1.162	0.126
Expression of LINC00261 (high vs. low)	0.551	0.323–0.940	0.029*

*P < 0.05